Have questions? Visit https://www.reddit.com/r/SNPedia

i3002759(A;A)

From SNPedia

TTR-Related Cardiac Amyloidosis
is agenotype
ofI3002759
mentionedby
Magnitude5
ReputeBad
Geno Mag Summary
(A;A) 5 TTR-Related Cardiac Amyloidosis
(A;G) 5 TTR-Related Cardiac Amyloidosis
(G;G) 0 normal

A person with one or two copies of the (A) allele of this SNP is at significantly higher (by about 2 - 3 fold) risk of developing cardiac amyloidosis, in which levels of the transthyretin protein build up and may lead to heart failure, especially with increasing age.