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rs1042580

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(A;A) 0
Make rs1042580(A;G)
Make rs1042580(G;G)
ReferenceGRCh38 38.1/141
Chromosome20
Position23046984
GeneTHBD
is asnp
is mentioned by
dbSNPrs1042580
ebirs1042580
HLIrs1042580
Exacrs1042580
Varsomers1042580
Maprs1042580
PheGenIrs1042580
hapmaprs1042580
1000 genomesrs1042580
hgdprs1042580
ensemblrs1042580
gopubmedrs1042580
geneviewrs1042580
scholarrs1042580
googlers1042580
pharmgkbrs1042580
gwascentralrs1042580
openSNPrs1042580
23andMers1042580
23andMe allrs1042580
SNP Nexus

SNPshotrs1042580
SNPdbers1042580
MSV3drs1042580
GWAS Ctlgrs1042580
GMAF0.2801
Max Magnitude0
? (A;A) (A;G) (G;G) 28
linked to Cardiovascular Events

Several CVD risk variants were identified: In women, the combination of F5 rs7542281 × THBD rs1042580, together with three single F5 SNPs, was associated with CVD events. Among men, PROC rs1041296, when combined with either ICAM1 rs5030341 or F5 rs2269648, was associated with total mortality. As a single variant, PROC rs1401296, together with the F5 Leiden mutation, was associated with ischemic stroke events.[PMID 17677000OA-icon.png]


[PMID 24602049] Association of gene polymorphisms with the risk of warfarin bleeding complications at therapeutic INR in patients with mechanical cardiac valves


[PMID 25225421] Single-Nucleotide Polymorphisms Within the Thrombomodulin Gene (THBD) Predict Mortality in Patients With Graft-Versus-Host Disease


[PMID 24816905OA-icon.png] Single nucleotide variants in the protein C pathway and mortality in dialysis patients