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rs10821936(C;C)

From SNPedia

Higher risk of childhood acute lymphoblastic leukemia
Is agenotype
ofrs10821936
GeneARID5B
Chromosome10
Position61,963,818
mentionedby
Magnitude2.5
ReputeBad
Geno Mag Summary
(C;C) 2.5 Higher risk of childhood acute lymphoblastic leukemia
(C;T) 2.1 Higher risk of childhood acute lymphoblastic leukemia
(T;T) normal

Consistently, when we further classified children into age groups of those aged less than 5 years, those aged 5 to 10 years, and those aged greater than 10 years, there was a trend for decreasing allelic odds ratio (ie, relative risk of ALL conferred by each copy of the C allele at rs10821936) as age increased: 2.01 (95% CI = 1.85 to 2.19), 1.8 (95% CI = 1.6 to 2.02), and 1.48 (95% CI = 1.3 to 1.68), respectively.

[PMID 23512250]