Have questions? Visit https://www.reddit.com/r/SNPedia

rs11209026(G;G)

From SNPedia

Normal, but higher risk for certain autoimmune diseases.
Is agenotype
ofrs11209026
GeneIL23R
Chromosome1
Position67,240,275
mentionedby
Magnitude1.1
ReputeBad
Geno Mag Summary
(A;A) 3 0.26x lower risk for certain autoimmune diseases.
(A;G) 2.5 0.26x lower risk for certain autoimmune diseases.
(G;G) 1.1 Normal, but higher risk for certain autoimmune diseases.

Almost everyone has this form, but it indicates a slightly higher risk of Ankylosing Spondylitis, Crohn's Disease (1.09x), Psoriasis (1.06x), and Ulcerative Colitis (1.06x). The risk is much greater than for the rare version. This is the interleukin-23 (IL-23) receptor.

[[Media:http://www.the-rheumatologist.org/details/article/2528901/Neutralizing_IL-23_and_Its_Targets_May_Improve_Ankylosing_Spondylitis.html] Neutralizing IL-23 and Its Targets May Improve Ankylosing Spondylitis

by Lara C. Pullen, PhD in The Rheumatologist newsmagazine ]