rs1127354(A;A)

Causative for ITPase deficiency; also, reduces risk of anemia due to ribivarin anti-hepatitis C virus therapy

Is a	genotype
of	rs1127354
Gene	ITPA
Chromosome	20
Position	3,213,196
mentioned	by

Magnitude

3.2

Repute

Bad

Geno	Mag	Summary
(A;A)	3.2	Causative for ITPase deficiency; also, reduces risk of anemia due to ribivarin anti-hepatitis C virus therapy
(A;C)	2	lower ITPA production; be aware if treated with mercaptopurine
(C;C)	0	common in clinvar

Causative for ITPase deficiency; be aware of higher neutropenia risk if treated with mercaptopurine; yet also, reduced risk of anemia when subject to ribivarin-based anti-hepatitis C virus therapy.