Results of this 20,000+ person study suggested that each minor (risk) allele at these two SNPs increases the hazard ratio for total stroke about 1.31 (CI: 1.19 - 1.44) and for ischemic stroke by about 1.40 (CI: 1.27 - 1.56). The corresponding population attributable risks were 11 to 13% for total stroke and 14 to 17% for ischemic stroke, which is fairly high for this sort of SNP. 10.1056/NEJMoa0900094
[PMID 21722921] NINJ2 polymorphism is associated with ischemic stroke in Chinese Han population
[PMID 21832970] Association between two key SNPs on chromosome 12p13 and ischemic stroke in Chinese Han population
[PMID 22011019] Association of two single nucleotide polymorphisms from genomewide association studies with clinical phenotypes of cerebral ischemia
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[PMID 19369658] Genomewide association studies of stroke.
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[PMID 20957003] [Strong association between the NINJ2 gene polymorphism and the susceptibility of stroke in Chinese Han population in Fangshan district].
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[PMID 23270316] Association between the Single Nucleotide Polymorphism rs12425791 and Ischemic Stroke in Chinese Populations: New Data and Meta-analysis
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