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rs16947078

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 0 common
(A;G) possible risk for allergic asthma
(G;G) 8x risk for allergic asthma
ReferenceGRCh38 38.1/141
Chromosome17
Position47748134
GeneTBX21
is asnp
is mentioned by
dbSNPrs16947078
ebirs16947078
HLIrs16947078
Exacrs16947078
Varsomers16947078
Maprs16947078
PheGenIrs16947078
hapmaprs16947078
1000 genomesrs16947078
hgdprs16947078
ensemblrs16947078
gopubmedrs16947078
geneviewrs16947078
scholarrs16947078
googlers16947078
pharmgkbrs16947078
gwascentralrs16947078
openSNPrs16947078
23andMers16947078
23andMe allrs16947078
SNP Nexus

SNPshotrs16947078
SNPdbers16947078
MSV3drs16947078
GWAS Ctlgrs16947078
GMAF0.146
Max Magnitude0
? (A;A) (A;G) (G;G) 28

A large study of Caucasian children has identified this SNP in the TBX21 gene (and one other, rs11650354) as defining a haplotype associated with increased risk for allergic asthma. [PMID 17949803]

The odds ratio associated with rs16947078(G;G) homozygotes compared to rs16947078(A;A) homozygotes for allergic asthma is reported to be 8.13 (CI: 2.5-26.9). Heterozygotes may be at slightly higher risk. [PMID 17949803]