rs17228212
Orientation | plus |
Stabilized | plus |
Geno | Mag | Summary |
---|---|---|
(C;C) | 2 | >1.26x increased risk for heart disease |
(C;T) | 2 | 1.26x increased risk for heart disease |
(T;T) | 0 | normal |
Reference | GRCh38 38.1/141 |
Chromosome | 15 |
Position | 67166301 |
Gene | SMAD3 |
is a | snp |
is | mentioned by |
dbSNP | rs17228212 |
dbSNP (classic) | rs17228212 |
ClinGen | rs17228212 |
ebi | rs17228212 |
HLI | rs17228212 |
Exac | rs17228212 |
Gnomad | rs17228212 |
Varsome | rs17228212 |
LitVar | rs17228212 |
Map | rs17228212 |
PheGenI | rs17228212 |
Biobank | rs17228212 |
1000 genomes | rs17228212 |
hgdp | rs17228212 |
ensembl | rs17228212 |
geneview | rs17228212 |
scholar | rs17228212 |
rs17228212 | |
pharmgkb | rs17228212 |
gwascentral | rs17228212 |
openSNP | rs17228212 |
23andMe | rs17228212 |
SNPshot | rs17228212 |
SNPdbe | rs17228212 |
MSV3d | rs17228212 |
GWAS Ctlg | rs17228212 |
GMAF | 0.1561 |
Max Magnitude | 2 |
? | (C;C) (C;T) (T;T) | 28 |
---|---|---|
|
rs17228212 is a SNP found to be associated with heart disease by the German MI (Myocardial infarction) Family Study group in two populations. The odds ratio per allele is 1.26 (CI: 1.11-1.44, p=0.0178).[PMID 17634449]
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[PMID 19956433] Genetics of coronary artery disease: focus on genome-wide association studies.
[PMID 20017983] Evaluation of population impact of candidate polymorphisms for coronary heart disease in the Framingham Heart Study Offspring Cohort.
[PMID 20098575] Genetics and cardiovascular disease: Design and development of a DNA biobank.
[PMID 21804106] Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration.
[PMID 26110764] Characterization of SMAD3 Gene Variants for Possible Roles in Ventricular Septal Defects and Other Congenital Heart Diseases