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rs1800462(C;C)

From SNPedia
incapable of detoxifying certain drugs
Is agenotype
ofrs1800462
GeneTPMT
Chromosome6
Position18,143,724
mentionedby
Magnitude3.5
ReputeBad
Geno Mag Summary
(C;C) 3.5 incapable of detoxifying certain drugs
(C;G) 2.5 detoxifying ability of certain drugs may be diminished
(G;G) 0 normal for 23andMe

poor drug metabolism of some medications.

potentially encoding a variant incapable of detoxifying byproducts of certain antineoplastic and immunosuppressant drugs.

http://blog.23andme.com/health-traits/do-you-know-how-youll-respond-to-thiopurine-medications/