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rs1800497(C;C)

From SNPedia
Normal (A2/A2)
Is agenotype
ofrs1800497
GeneANKK1
Chromosome11
Position113,400,106
mentionedby
Magnitude3
ReputeGood
Geno Mag Summary
(C;C) 3 Normal (A2/A2)
(C;T) 2.9 A1/A2: Bad at avoidance of errors. 0.5x lower OCD risk, 0.87x lower Tardive Diskinesia risk, higher ADHD risk. More Alcohol Dependence. Lower risk of Postoperative Nausea. Increased obesity. Bupropion is not effective for smoking cessation.
(T;T) 4 A1/A1: Bad at avoidance of errors. 0.25x lower OCD; 0.56x lower Tardive Diskinesia; higher ADHD; 1.4x Alcohol Dependence; lower Postoperative Nausea; Increased obesity; less pleasure response; Bupropion ineffective for smoking cessation.; 2.4x risk for adenoma recurrence.

Better avoidance of errors. Normal OCD risk, normal Tardive Dyskinesia risk, lower ADHD risk. Less Alcohol dependence. Higher risk of Postoperative Nausea. Lower obesity. Bupropion is effective.

This DRD2 TaqIA A2/A2 version causes a normal amount of Dopamine Receptors. Learns from mistakes more easily. Men may have a higher risk of Obsessive Compulsive Disorder but lower risk of ADHD. Women have higher Persistence. Higher risk of Tardive Diskinesia when taking dopamine receptor antagonists. Lower risk of alcoholism and smoking addiction. Faster recovery from traumatic brain injury. 1.6x risk of early postoperative nausea within 6 hours of surgery. Bupropion (Wellbutrin, Budeprion, Prexaton, Elontril, Aplenzin, Zyban, Voxra) works to quit smoking. Lower obesity due to increased pleasure response to food.