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rs2279345

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(T;T) 0 common in clinvar
Make rs2279345(C;C)
Make rs2279345(C;T)
ReferenceGRCh38 38.1/141
Chromosome19
Position41009797
GeneCYP2B6
is asnp
is mentioned by
dbSNPrs2279345
ebirs2279345
HLIrs2279345
Exacrs2279345
Varsomers2279345
Maprs2279345
PheGenIrs2279345
hapmaprs2279345
1000 genomesrs2279345
hgdprs2279345
ensemblrs2279345
gopubmedrs2279345
geneviewrs2279345
scholarrs2279345
googlers2279345
pharmgkbrs2279345
gwascentralrs2279345
openSNPrs2279345
23andMers2279345
23andMe allrs2279345
SNP Nexus

SNPshotrs2279345
SNPdbers2279345
MSV3drs2279345
GWAS Ctlgrs2279345
GMAF0.2998
Max Magnitude0
? (C;C) (C;T) (T;T) 28
[PMID 20639527OA-icon.png] Haplotype structure of CYP2B6 and association with plasma efavirenz concentrations in a Chilean HIV cohort

[PMID 21694616] CYP2B6 polymorphisms influence the plasma concentration and clearance of the methadone S-enantiomer.


ClinVar
Risk rs2279345(C;C)
Alt rs2279345(C;C)
Reference rs2279345(T;T)
Significance Drug-response
Disease efavirenz response - Metabolism/PK
Variation info
Gene CYP2B6
CLNDBN efavirenz response - Metabolism/PK
Reversed 0
HGVS NC_000019.9:g.41515702T>A
CLNSRC PharmGKB Clinical Annotation PharmGKB
CLNACC RCV000211199.1,