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rs2280090

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0
Make rs2280090(A;A)
Make rs2280090(A;G)
Make rs2280090(G;G)
ReferenceGRCh38 38.1/141
Chromosome20
Position3669558
GeneADAM33
is asnp
is mentioned by
dbSNPrs2280090
ebirs2280090
HLIrs2280090
Exacrs2280090
Varsomers2280090
Maprs2280090
PheGenIrs2280090
hapmaprs2280090
1000 genomesrs2280090
hgdprs2280090
ensemblrs2280090
gopubmedrs2280090
geneviewrs2280090
scholarrs2280090
googlers2280090
pharmgkbrs2280090
gwascentralrs2280090
openSNPrs2280090
23andMers2280090
23andMe allrs2280090
SNP Nexus

SNPshotrs2280090
SNPdbers2280090
MSV3drs2280090
GWAS Ctlgrs2280090
GMAF0.146
Max Magnitude0
rs2280090, a SNP in the ADAM33 gene, has been linked to a predisposition to asthma and bronchial hyperresponsiveness. [PMID 12110844, PMID 14564349]
Neighborrs2280089
Distance78

[PMID 19236319] Smoke exposure interacts with ADAM33 polymorphisms in the development of lung function and hyperresponsiveness


[PMID 16519819OA-icon.png] Analysis of polymorphisms in 16 genes in type 1 diabetes that have been associated with other immune-mediated diseases.


[PMID 16784537OA-icon.png] The role of polymorphisms in ADAM33, a disintegrin and metalloprotease 33, in childhood asthma and lung function in two German populations.


[PMID 17878941OA-icon.png] ADAM33, a new candidate for psoriasis susceptibility.


[PMID 18778489OA-icon.png] Association of ADAM33 gene polymorphisms with adult allergic asthma and rhinitis in a Chinese Han population.


[PMID 19146844] ADAM33 genetic polymorphisms and risk of atopic dermatitis among Japanese children.


GET Evidence
ADAM33-P774S
aa_change Pro774Ser
aa_change_short P774S
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.1318
summary



[PMID 22583515] ADAM33 polymorphisms, smoking and asthma in Japanese women: the Kyushu Okinawa Maternal and Child Health Study.


[PMID 22851202] Association between ADAM33 T1 polymorphism and susceptibility to asthma in Asians.


[PMID 22871616] T1 and T2 ADAM33 single nucleotide polymorphisms and the risk of childhood asthma in a Saudi Arabian population: a pilot study.


[PMID 23380143] A disintegrin and metalloprotease 33 (ADAM33) gene polymorphisms and the risk of asthma: a meta-analysis.


[PMID 25691950OA-icon.png] Association of ADAM33 gene polymorphisms with allergic asthma