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rs2395029(G;T)

From SNPedia

HLA-B*5701 carrier
Is agenotype
ofrs2395029
GeneHCP5
Chromosome6
Position31,464,003
mentionedby
Magnitude3.2
ReputeBad
Geno Mag Summary
(G;G) 4 HLA-B*5701 homozygote; high risk for hypersensitivity to various drugs including abacavir; 2x psoriasis risk; see details
(G;T) 3.2 HLA-B*5701 carrier
(T;T) 0 common

risk for hypersensitivity to various drugs including abacavir

This genotype is associated with an HIV viral load 1 log (10 fold) lower than the most common genotype (rs2395029(T;T)). [PMID 17641165]

Possible 2x higher risk for psoriasis

See also rs2395029 and HIV.

The (G) allele frequency is only 0.05 which means only about 1 in 10 people have this genotype.