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rs27048

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 2x risk of severe alcohol withdrawal
(C;T) 0 normal
(T;T) 0 normal
ReferenceGRCh38 38.1/141
Chromosome5
Position1412530
GeneSLC6A3
is asnp
is mentioned by
dbSNPrs27048
ebirs27048
HLIrs27048
Exacrs27048
Varsomers27048
Maprs27048
PheGenIrs27048
hapmaprs27048
1000 genomesrs27048
hgdprs27048
ensemblrs27048
gopubmedrs27048
geneviewrs27048
scholarrs27048
googlers27048
pharmgkbrs27048
gwascentralrs27048
openSNPrs27048
23andMers27048
23andMe allrs27048
SNP Nexus

SNPshotrs27048
SNPdbers27048
MSV3drs27048
GWAS Ctlgrs27048
GMAF0.3255
Max Magnitude0
? (C;C) (C;T) (T;T) 28

[rs27048]], a SNP in the dopamine transporter SLC6A3 gene, has been associated with more severe symptoms upon alcohol withdrawal, such as seizures, in a study of 250 Caucasian alcohol-dependent patients. Two haplotypes appear to be tagged by this SNP and a neighbor, rs27072. [PMID 18070248]

Variations in the DAT1 gene may affect the inattentive subtype of ADHD.[PMID 20800641]


[PMID 16537431OA-icon.png] A dopamine transporter gene functional variant associated with cocaine abuse in a Brazilian sample.