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rs2853498(G;G)

From SNPedia

12308+, MT-Haplogroup U or K.
Is agenotype
ofrs2853498
GeneMT-TL2
ChromosomeMT
Position12,308
mentionedby
Magnitude1.5
ReputeBad
Geno Mag Summary
(A;A) 0.1 12308-, not MT-Haplogroup U or K.
(G;G) 1.5 12308+, MT-Haplogroup U or K.

One of the three SNPs required for Mitochondrial haplogroup U or K is present. This also indicates a mutation in the mitochondrial gene for building proteins containing the amino acid Leucine. It has been linked to a 1.5x increased risk of Age-related Macular Degeneration.