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rs2854128(A;A)

From SNPedia

G2706A+, probably MT-Haplogroup H.
Is agenotype
ofrs2854128
GeneMT-RNR2
ChromosomeMT
Position2,706
mentionedby
Magnitude1
ReputeBad
Geno Mag Summary
(A;A) 1 G2706A+, probably MT-Haplogroup H.
(G;G) 0.1 G2706A-, not MT-Haplogroup H

One of the 2 ancestral mitochondrial mutations needed for mitochondrial Haplogroup H. This is a non-synonymous mutation in the mitochondrial ribosome, and possibly in the neuroprotective protein humanin. Haplogroup H has been associated with increased risk of age-related neurological diseases, suggesting that this mutation (or some other) may slightly reduce the effectiveness of mitochondria or humanin.