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rs3211371

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0 common in complete genomics
Make rs3211371(C;T)
Make rs3211371(T;T)
ReferenceGRCh38 38.1/141
Chromosome19
Position41016810
GeneCYP2B6
is asnp
is mentioned by
dbSNPrs3211371
ebirs3211371
HLIrs3211371
Exacrs3211371
Varsomers3211371
Maprs3211371
PheGenIrs3211371
hapmaprs3211371
1000 genomesrs3211371
hgdprs3211371
ensemblrs3211371
gopubmedrs3211371
geneviewrs3211371
scholarrs3211371
googlers3211371
pharmgkbrs3211371
gwascentralrs3211371
openSNPrs3211371
23andMers3211371
23andMe allrs3211371
SNP Nexus

SNPshotrs3211371
SNPdbers3211371
MSV3drs3211371
GWAS Ctlgrs3211371
GMAF0.05051
Max Magnitude0
rs3211371, also known as 1459C>T, is a SNP encoding the CYP2B6*5 allele of the CYP2B6 gene.




[PMID 21886015] Cytochrome P450 CYP2B6 genotypes and haplotypes in a Colombian population: identification of novel variant CYP2B6 alleles

[PMID 19076156OA-icon.png] Polymorphisms of drug-metabolizing enzymes (GST, CYP2B6 and CYP3A) affect the pharmacokinetics of thiotepa and tepa.


[PMID 19154420OA-icon.png] The impact of cytokines on the expression of drug transporters, cytochrome P450 enzymes and chemokine receptors in human PBMC.


[PMID 20459744OA-icon.png] Cyclophosphamide-metabolizing enzyme polymorphisms and survival outcomes after adjuvant chemotherapy for node-positive breast cancer: a retrospective cohort study.


[PMID 21172166OA-icon.png] Pharmacogenetics of antidepressant response.


GET Evidence
CYP2B6-R487C
aa_change Arg487Cys
aa_change_short R487C
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.0877487
summary



[PMID 23249875] Contribution of CYP2B6 alleles in explaining extreme (S)-methadone plasma levels: a CYP2B6 gene resequencing study


[PMID 24260284OA-icon.png] CYP2B6 Non-Coding Variation Associated with Smoking Cessation Is Also Associated with Differences in Allelic Expression, Splicing, and Nicotine Metabolism Independent of Common Amino-Acid Changes


[PMID 23133420OA-icon.png] Pharmacogenomic Diversity among Brazilians: Influence of Ancestry, Self-Reported Color, and Geographical Origin.


[PMID 25677220] Cytochrome P450 2B6*5 Increases Relapse after Cyclophosphamide-containing Conditioning and Autologous Transplantation for Lymphoma


[PMID 25428516] Effects of CYP2B6 genetic polymorphisms in patients receiving cyclophosphamide combination chemotherapy for breast cancer