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rs3766379

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0 normal
(C;T) 1.37x increased risk for rheumatoid arthritis
(T;T) 1.9x increased risk for rheumatoid arthritis
ReferenceGRCh38 38.1/141
Chromosome1
Position160837925
GeneCD244
is asnp
is mentioned by
dbSNPrs3766379
ebirs3766379
HLIrs3766379
Exacrs3766379
Varsomers3766379
Maprs3766379
PheGenIrs3766379
hapmaprs3766379
1000 genomesrs3766379
hgdprs3766379
ensemblrs3766379
gopubmedrs3766379
geneviewrs3766379
scholarrs3766379
googlers3766379
pharmgkbrs3766379
gwascentralrs3766379
openSNPrs3766379
23andMers3766379
23andMe allrs3766379
SNP Nexus

SNPshotrs3766379
SNPdbers3766379
MSV3drs3766379
GWAS Ctlgrs3766379
GMAF0.4656
Max Magnitude0
? (C;C) (C;T) (T;T) 28
Two SNPs on ch 1q in the CD244 gene, rs3766379 and rs6682654, were found to be associated with risk for rheumatoid arthritis in two independent Japanese cohorts (p = 3.23 x 10e-8) and p = 7.45 x 10e-8). The odds ratio reported for the more common rs3766379(T) allele was 1.37 (CI: 1.18-1.59, p = 0.0001).[PMID 18794858]
OMIM180300
DescRHEUMATOID ARTHRITIS; RA
Variant
Relatedalso
OMIM605554
DescCD244 ANTIGEN; CD244
Variant
Relatedalso
OMIM605554
Desc
Variant0001
Relatedalso


[PMID 20437071] Single nucleotide polymorphisms of CD244 gene predispose to renal and neuropsychiatric manifestations with systemic lupus erythematosus.


ClinVar
Risk rs3766379(C;C)
Alt rs3766379(C;C)
Reference rs3766379(T;T)
Significance Other
Disease Rheumatoid arthritis
Variation info
Gene CD244
CLNDBN Rheumatoid arthritis
Reversed 0
HGVS NC_000001.10:g.160807715T>C
CLNSRC OMIM Allelic Variant
CLNACC RCV000005173.2,