Have questions? Visit https://www.reddit.com/r/SNPedia

rs4532

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0
Make rs4532(C;T)
Make rs4532(T;T)
ReferenceGRCh38 38.1/141
Chromosome5
Position175443147
GeneDRD1
is asnp
is mentioned by
dbSNPrs4532
ebirs4532
HLIrs4532
Exacrs4532
Varsomers4532
Maprs4532
PheGenIrs4532
hapmaprs4532
1000 genomesrs4532
hgdprs4532
ensemblrs4532
gopubmedrs4532
geneviewrs4532
scholarrs4532
googlers4532
pharmgkbrs4532
gwascentralrs4532
openSNPrs4532
23andMers4532
23andMe allrs4532
SNP Nexus

SNPshotrs4532
SNPdbers4532
MSV3drs4532
GWAS Ctlgrs4532
GMAF0.2534
Max Magnitude0
? (C;C) (C;T) (T;T) 28
Implicated as part of a haplotype of the dopamine D1 receptor DRD1 gene associated with autism spectrum disorders in families having only affected males. The haplotype is rs265981(C)-rs4532(A)-rs686(T) as published, though not necessarily as oriented in dbSNP.[PMID 18205172]
Neighborrs265981
Distance752
OMIM181500
DescSCHIZOPHRENIA; SCZD
Variant
Relatedalso
OMIM188890
DescTOBACCO ADDICTION, SUSCEPTIBILITY TO
Variant
Relatedalso
OMIM126449
DescDOPAMINE RECEPTOR D1; DRD1
Variant
Relatedalso


[PMID 20382433] No genetic association between dopamine D1 receptor gene and [early onset] schizophrenia

[PMID 20456319] Association of polymorphisms in the BDNF, DRD1 and DRD3 genes with tobacco smoking in schizophrenia


[PMID 22093926] [Association analysis between dopamine D1 receptor gene and symptom quantitative trait of schizophrenia]


[PMID 15087492OA-icon.png] A new approach to SNP genotyping with fluorescently labeled mononucleotides.


[PMID 17092969] Association study of four dopamine D1 receptor gene polymorphisms and clozapine treatment response.


[PMID 18092181] Significant association of DRD1 with nicotine dependence.


[PMID 18341651] A haplotype of the DRD1 gene is associated with alcohol dependence.


[PMID 18366720OA-icon.png] Association of dopaminergic pathway gene polymorphisms with chronic renal insufficiency among Asian Indians with type-2 diabetes.


[PMID 21181138] Analysis of genetic variations in the dopamine D1 receptor (DRD1) gene and antipsychotics-induced tardive dyskinesia in schizophrenia.


[PMID 21955727] An association study between dopamine D1 receptor gene polymorphisms and the risk of schizophrenia.


[PMID 23036699] DRD1 rs4532 polymorphism: A potential pharmacogenomic marker for treatment response to antipsychotic drugs


[PMID 25018632OA-icon.png] Association of dopamine D1 receptor gene polymorphism with schizophrenia: a meta-analysis


[PMID 25660313] Meta-analysis of six genes (BDNF, DRD1, DRD3, DRD4, GRIN2B and MAOA) involved in neuroplasticity and the risk for alcohol dependence