|?|| (A;A) (A;G) (G;G) ||28|
Implicated as part of a haplotype of the dopamine D1 receptor DRD1 gene associated with autism spectrum disorders in families having only affected males. The haplotype is rs265981(C)-rs4532(A)-rs686(T) as published, though not necessarily as oriented in dbSNP.[PMID 18205172]
|Desc||TOBACCO ADDICTION, SUSCEPTIBILITY TO|
] Association of polymorphisms in the BDNF, DRD1 and DRD3 genes with tobacco smoking in schizophrenia
[PMID 18092181] Significant association of DRD1 with nicotine dependence.
[PMID 18341651] A haplotype of the DRD1 gene is associated with alcohol dependence.
[PMID 18937842] The influence of serotonin- and other genes on impulsive behavioral aggression and cognitive impulsivity in children with attention-deficit/hyperactivity disorder (ADHD): Findings from a family-based association test (FBAT) analysis.
[PMID 19135651] Differential allelic expression of dopamine D1 receptor gene (DRD1) is modulated by microRNA miR-504.
[PMID 19500151] Heroin addiction in African Americans: a hypothesis-driven association study.
[PMID 21332319] Gene-gene interaction analyses between NMDA receptor subunit and dopamine receptor gene variants and clozapine response.
[PMID 21955727] An association study between dopamine D1 receptor gene polymorphisms and the risk of schizophrenia.
[PMID 22574669] Dopamine receptors D1 and D2 are related to observed maternal behavior.