Have questions? Visit https://www.reddit.com/r/SNPedia

rs6318(C;C)

From SNPedia

1.4x increased risk for cardiac events in patients; apparently stress (cortisol) related
Is agenotype
ofrs6318
GeneHTR2C
ChromosomeX
Position114,731,326
mentionedby
Magnitude2.5
ReputeBad
Geno Mag Summary
(C;C) 2.5 1.4x increased risk for cardiac events in patients; apparently stress (cortisol) related
(C;G) 0 Female only, since on X ch; appears to mostly be = to common (G;G) genotype
(G;G) 0 common in clinvar

See rs6318. Male catheterization patients at ~1.2x increased risk for subsequent cardiac events, females at ~1.6x increased risk. Likely stronger emotional response to stress, and apparently (slightly?) higher risk for affective disorders (major depressive and bipolar disorders). Poorer lipid profiles have also been reported.