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rs6413458

From SNPedia

Orientationminus
Stabilizedplus
Geno Mag Summary
(C;C) 0 common in clinvar
(G;G) 0
Make rs6413458(C;T)
Make rs6413458(T;T)
ReferenceGRCh38 38.1/142
Chromosome2
Position21008720
GeneAPOB
is asnp
is mentioned by
dbSNPrs6413458
ebirs6413458
HLIrs6413458
Exacrs6413458
Varsomers6413458
Maprs6413458
PheGenIrs6413458
hapmaprs6413458
1000 genomesrs6413458
hgdprs6413458
ensemblrs6413458
gopubmedrs6413458
geneviewrs6413458
scholarrs6413458
googlers6413458
pharmgkbrs6413458
gwascentralrs6413458
openSNPrs6413458
23andMers6413458
23andMe allrs6413458
SNP Nexus

SNPshotrs6413458
SNPdbers6413458
MSV3drs6413458
GWAS Ctlgrs6413458
GMAF0.01423
Max Magnitude0
? (C;C) (C;T) (T;T) 28
GWAS snp
PMID [PMID 23118302]
Trait Lipoprotein-associated phospholipase A2 activity and mass
Title Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.
Risk Allele T
P-val 2E-7
Odds Ratio .04 [0.0088-0.0708] ng/ml decrease


ClinVar
Risk rs6413458(T;T)
Alt rs6413458(T;T)
Reference rs6413458(C;C)
Significance Non-pathogenic
Disease Hypercholesterolemia Hypobetalipoproteinemia
Variation info
Gene APOB
CLNDBN Hypercholesterolemia, autosomal dominant, type B Hypobetalipoproteinemia, familial, 1
Reversed 1
HGVS NC_000002.11:g.21231592G>A
CLNSRC
CLNACC RCV000231970.1,