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rs67376798

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 3.5 5-fluorouracil toxicity
(A;T) 2 carrier of a null DPYD allele
(T;T) 0 common/normal
ReferenceGRCh38 38.1/142
Chromosome1
Position97082391
GeneDPYD
is asnp
is mentioned by
dbSNPrs67376798
ebirs67376798
HLIrs67376798
Exacrs67376798
Varsomers67376798
Maprs67376798
PheGenIrs67376798
hapmaprs67376798
1000 genomesrs67376798
hgdprs67376798
ensemblrs67376798
gopubmedrs67376798
geneviewrs67376798
scholarrs67376798
googlers67376798
pharmgkbrs67376798
gwascentralrs67376798
openSNPrs67376798
23andMers67376798
23andMe allrs67376798
SNP Nexus

SNPshotrs67376798
SNPdbers67376798
MSV3drs67376798
GWAS Ctlgrs67376798
Max Magnitude3.5

rs67376798, also known as c.2846 A>T, is a SNP in the DPYD gene on chromosome 1.

Note that the "A>T" term in the name used in the literature for this SNP can be confusing, since the gene is in reverse orientation to the chromosome strand on the reference genome.


ClinVar
Risk rs67376798(A;A)
Alt rs67376798(A;A)
Reference rs67376798(T;T)
Significance Drug-response
Disease not provided tegafur response - Toxicity/ADR capecitabine response - Toxicity/ADR fluorouracil response - Toxicity/ADR
Variation info
Gene DPYD
CLNDBN not provided tegafur response - Toxicity/ADR capecitabine response - Toxicity/ADR fluorouracil response - Toxicity/ADR
Reversed 0
HGVS NC_000001.10:g.97547947T>A
CLNSRC PharmGKB Clinical Annotation PharmGKB
CLNACC RCV000086452.1, RCV000211225.1, RCV000211280.1, RCV000211407.1,