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rs6897876

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 1.2 slight increase in testicular cancer risk for men
(C;T) 1.1 slight increase in testicular cancer risk for men
(T;T) 0 normal
ReferenceGRCh38 38.1/141
Chromosome5
Position142308074
is asnp
is mentioned by
dbSNPrs6897876
ebirs6897876
HLIrs6897876
Exacrs6897876
Varsomers6897876
Maprs6897876
PheGenIrs6897876
hapmaprs6897876
1000 genomesrs6897876
hgdprs6897876
ensemblrs6897876
gopubmedrs6897876
geneviewrs6897876
scholarrs6897876
googlers6897876
pharmgkbrs6897876
gwascentralrs6897876
openSNPrs6897876
23andMers6897876
23andMe allrs6897876
SNP Nexus

SNPshotrs6897876
SNPdbers6897876
MSV3drs6897876
GWAS Ctlgrs6897876
GMAF0.4986
Max Magnitude1.2
? (C;C) (C;T) (T;T) 28
Testicular germ cell tumor risk I("TGCT"; i.e. testicular cancer risk) was increased 40% per copy of the major allele (C) at rs4324715 and rs6897876 (OR = 1.37, CI: 1.14–1.64; OR = 1.39, CI: 1.16–1.66, respectively), based on a genome-wide scan of 277 primarily Caucasian TGCT cases and 919 controls. Men who have two copies of the common version of the sprouty 4 SPRY4 gene have a 1.5-fold higher risk of testicular cancer than men who have two copies of the less common or minor version of the gene.[PMID 19483682OA-icon.png]