|(G;G)||0||common in clinvar|
[PMID 20010782] Influence of ghrelin gene polymorphisms on hypertension and atherosclerotic disease
|Disease||Obesity Metabolic syndrome|
|CLNDBN||Obesity, age at onset of Metabolic syndrome, susceptibility to|
|CLNSRC||OMIM Allelic Variant|
[PMID 16204371] Variants in the ghrelin gene are associated with metabolic syndrome in the Old Order Amish.
[PMID 16921495] Possible role of preproghrelin gene polymorphisms in susceptibility to bulimia nervosa.
[PMID 17357083] Medical sequencing at the extremes of human body mass.
[PMID 17389697] Examining the candidacy of ghrelin as a gene responsible for variation in adult stature in a United Kingdom population with type 2 diabetes.
[PMID 18249219] Interaction of single nucleotide polymorphisms in ADRB2, ADRB3, TNF, IL6, IGF1R, LIPC, LEPR, and GHRL with physical activity on the risk of type 2 diabetes mellitus and changes in characteristics of the metabolic syndrome: The Finnish Diabetes Prevention Study.
[PMID 18778477] Genomic variation in myeloma: design, content, and initial application of the Bank On A Cure SNP Panel to detect associations with progression-free survival.
[PMID 19041386] Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.
[PMID 19077438] Analysis of 30 genes (355 SNPS) related to energy homeostasis for association with adiposity in European-American and Yup'ik Eskimo populations.
[PMID 19593725] Association of maternally inherited GNAS alleles with African-American male birth weight.
[PMID 20191112] The Genetics of Anorexia Nervosa: Current Findings and Future Perspectives.
[PMID 20586762] Genetic variation of the ghrelin signaling system in females with severe alcohol dependence.
[PMID 21448464] The ghrelin signalling system is involved in the consumption of sweets.
|qualified_impact||Insufficiently evaluated not reviewed|
[PMID 23257630] Preproghrelin gene polymorphisms in obese Japanese women. Minor homozygotes are light eaters, do not prefer protein or fat, and apparently have a poor appetite.
[PMID 25868387] The association between rs4684677 T/A polymorphism in preproghrelin gene and predisposition to autoimmune thyroid diseases in children
[PMID 26059200] Genetic variation of the growth hormone secretagogue receptor gene is associated with alcohol use disorders identification test scores and smoking