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rs8187710

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) 0 common on affy axiom data
Make rs8187710(A;A)
Make rs8187710(A;G)
ReferenceGRCh38 38.1/142
Chromosome10
Position99851537
GeneABCC2
is asnp
is mentioned by
dbSNPrs8187710
ebirs8187710
HLIrs8187710
Exacrs8187710
Varsomers8187710
Maprs8187710
PheGenIrs8187710
hapmaprs8187710
1000 genomesrs8187710
hgdprs8187710
ensemblrs8187710
gopubmedrs8187710
geneviewrs8187710
scholarrs8187710
googlers8187710
pharmgkbrs8187710
gwascentralrs8187710
openSNPrs8187710
23andMers8187710
23andMe allrs8187710
SNP Nexus

SNPshotrs8187710
SNPdbers8187710
MSV3drs8187710
GWAS Ctlgrs8187710
GMAF0.06979
Max Magnitude0
? (A;A) (A;G) (G;G) 28

[PMID 19842932] Association between ABCC2 polymorphism and lopinavir accumulation in peripheral blood mononuclear cells of HIV-infected patients




[PMID 17997497] Association of the multidrug-resistance-associated protein gene (ABCC2) variants with intrahepatic cholestasis of pregnancy.


[PMID 18176959OA-icon.png] Increased susceptibility for intrahepatic cholestasis of pregnancy and contraceptive-induced cholestasis in carriers of the 1331T>C polymorphism in the bile salt export pump.


[PMID 18395921OA-icon.png] Role of ABCC2 common variants in intrahepatic cholestasis of pregnancy.


[PMID 18926681] Polymorphisms of MRP2 (ABCC2) are associated with susceptibility to nonalcoholic fatty liver disease.


[PMID 22027652] Functional defect caused by the 4544G>A SNP in ABCC2: potential impact for drug cellular disposition.


GET Evidence
ABCC2-C1515Y
aa_change Cys1515Tyr
aa_change_short C1515Y
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.0960216
summary



[PMID 23069858] Impact of ABCC2 polymorphisms on high-dose methotrexate pharmacokinetics in patients with lymphoid malignancy.