|Women have 10x risk of Endometriosis, but half the risk of Endometrial Cancer and 0.76x less cognitive impairment.|
|| Women have lower risk of Endometriosis but normal risk for Endometrial Cancer, and more cognitive impairment with age.
|| Women have normal (lower) risk of Endometriosis, 0.75x lower risk of Endometrial Cancer, and normal (higher) risk of cognitive impairment.
|| Women have 10x risk of Endometriosis, but half the risk of Endometrial Cancer and 0.76x less cognitive impairment.
Men have zero risk, but can pass it on to daughters. Endometriosis means that womb tissue grows outside the womb. This SNP is a change in Estrogen Receptor 1 (alpha). It also lowers risk of cognitive impairment in aging women - on the East Boston Memory Test immediate recall test, women with this had about 1.5 to 2.0 times greater odds of remembering story elements.[PMID 16949394]