Normal, but higher risk for certain autoimmune diseases. |
Geno
|
Mag
|
Summary
|
(A;A)
|
3
|
0.26x lower risk for certain autoimmune diseases.
|
(A;G)
|
2.5
|
0.26x lower risk for certain autoimmune diseases.
|
(G;G)
|
1.1
|
Normal, but higher risk for certain autoimmune diseases.
|
Almost everyone has this form, but it indicates a slightly higher risk of Ankylosing Spondylitis, Crohn's Disease (1.09x), Psoriasis (1.06x), and Ulcerative Colitis (1.06x). The risk is much greater than for the rare version. This is the interleukin-23 (IL-23) receptor.
[[Media:http://www.the-rheumatologist.org/details/article/2528901/Neutralizing_IL-23_and_Its_Targets_May_Improve_Ankylosing_Spondylitis.html]
Neutralizing IL-23 and Its Targets May Improve Ankylosing Spondylitis
by Lara C. Pullen, PhD in The Rheumatologist newsmagazine ]