rs2070744(T;T)
From SNPedia
| cardiovascular differences |
| Is a | genotype |
| of | rs2070744 |
| Gene | NOS3 |
| Chromosome | 7 |
| Position | 150,992,991 |
| mentioned | by |
| Magnitude | 2.1 |
| Repute | Good |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0.1 | increased prostate cancer risk |
| (C;T) | None | |
| (T;T) | 2.1 | cardiovascular differences |
This is found in high frequency male athletes from power sports such as jumpers, throwers, and sprinters. [PMID 19701646]
There may be negative health consequences with increased risk of cardiovascular disorders.[PMID 16979000] and response
Mexicans with this SNP, and also a T at rs1800783, have lower LDL cholesterol.
People with this SNP, and also a T at rs1800783, may be less responsive to hypnosis.[PMID 19853644]
Notably, this SNP does not change the amino acid (it is in the promoter region and doesn't encode the protein's amino acid sequence). The population frequencies in HapMap are incorrect.
