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rs9960767

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 0 normal
(A;C) 1.2 1.2x increased risk for schizophrenia
(C;C) 1.4 1.4x increased risk for schizophrenia
ReferenceGRCh38 38.1/141
Chromosome18
Position55487771
GeneTCF4
is asnp
is mentioned by
dbSNPrs9960767
dbSNP (classic)rs9960767
ClinGenrs9960767
ebirs9960767
HLIrs9960767
Exacrs9960767
Gnomadrs9960767
Varsomers9960767
LitVarrs9960767
Maprs9960767
PheGenIrs9960767
Biobankrs9960767
1000 genomesrs9960767
hgdprs9960767
ensemblrs9960767
geneviewrs9960767
scholarrs9960767
googlers9960767
pharmgkbrs9960767
gwascentralrs9960767
openSNPrs9960767
23andMers9960767
SNPshotrs9960767
SNPdbers9960767
MSV3drs9960767
GWAS Ctlgrs9960767
GMAF0.08586
Max Magnitude1.4
? (A;A) (A;C) (C;C) 28


23andMe blog schizophrenia

  • rs3131296(C) increased the odds of schizophrenia by 1.19x
  • rs12807809(T) increased the odds of schizophrenia by 1.15x
  • rs9960767(C) increased the odds of schizophrenia by 1.23 times.
GWAS snp
PMID [PMID 19571808OA-icon.png]
Trait Schizophrenia
Title Common variants conferring risk of schizophrenia
Risk Allele C
P-val 4E-9
Odds Ratio 1.23 [NR]
OMIM181500
Desc
Variant
Relatedalso


[PMID 21543597OA-icon.png] The Schizophrenia Risk Allele C of the TCF4 rs9960767 Polymorphism Disrupts Sensorimotor Gating in Schizophrenia Spectrum and Healthy Volunteers


[PMID 21812098OA-icon.png] Association between TCF4 and schizophrenia does not exert its effect by common nonsynonymous variation or by influencing cis-acting regulation of mRNA expression in adult human brain


[PMID 22451930OA-icon.png] Schizophrenia risk polymorphisms in the TCF4 gene interact with smoking in the modulation of auditory sensory gating


[PMID 20485477OA-icon.png] New Genetic Findings in Schizophrenia: Is there Still Room for the Dopamine Hypothesis of Schizophrenia?


[PMID 21228604] Novel schizophrenia risk gene TCF4 influences verbal learning and memory functioning in schizophrenia patients.


[PMID 21932083] Impact of TCF4 on the genetics of schizophrenia.



[PMID 22005930OA-icon.png] Genome-wide association study of Alzheimer's disease with psychotic symptoms.


[PMID 27305091] Genetic Association of TCF4 and AKT1 Gene Variants with the Age at Onset of Schizophrenia.