Have data from 23andMe or Ancestry? Make a report automatically with Promethease !


From SNPedia
Magnitude 3.3
Summary CYP2C19 Extensive or Ultra-Fast Metabolizer
Criteria Gs153/criteria

CYP2C19 Ultra-rapid metabolizer. Your body breaks down (i.e., detoxifies) certain medicines more quickly. It is possible that you may need a higher than average dosage of the medicines metabolized by CYP2C19 in order for them to be effective.

Medicines metabolized by CYP2C19 include the following:

  • some hormones (such as estrogens and progesterone)
  • anti-epileptics (such as diazepam, phenytoin, and phenobarbitone),
  • anti-depressants (such as amitriptyline and clomipramine)
  • Clopidogrel Plavix Prilosec Nexium Prevacid