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Repute

From SNPedia

Repute: The opinion generally held of someone or something; the state of being generally regarded in a particular way.

Repute as a parameter is applied to a (single) genotype, and it can be either Good, Bad, or Not Set (blank).

'Good' and 'Bad' are mostly self explanatory. However, it's worth stating that many genotypes have a bit of good and a bit of bad. These and many other genotypes should remain 'Not Set'. Sometimes that's because they're not distinctly Good or Bad (like eye color) or Ancestry, but usually it means no human has come along to do the classification yet. Often this is the right thing to do, because the published studies are still too new and unreplicated to be convincing. However if you read through the literature and feel that a particular genotype is convincingly good or bad, please edit the genotype page so that future users can benefit from your insight.

In a Promethease report, the Repute is represented by the colors outlining each genotype. Genotypes with good, bad, and not set reputes are outlined in green, red, and gray, respectively.

Traits and similiar neutral concepts like eye color should be left blank.

See also the related concept Magnitude

Good things

 MagnitudeSummary
rs237025(C;C)0common in clinvar
rs1061170(T;T)1.6lower risk for AMD, generally longer live than (C) allele carriers
rs1801253(G;G)0
rs17822931(T;T)2.5Dry earwax. No body odour. Likely Asian ancestry. Reduced colostrum.
rs16891982(C;C)1.1generally non-European, but if European, 7x more likely to have black hair
rs351855(C;C)0normal
rs713598(C;C)1.1Can taste bitter.
rs1726866(C;C)0.1can taste bitter
rs2227564(T;T)0common in clinvar
rs4680(G;G)2.5(warrior) multiple associations, see details
... further results

Bad things

 MagnitudeSummary
Gs32410Promethease is able to support this format, but we've identified this as coming from a vendor who's data is so error prone as to be worthless. This report is a correct representation of the data you gave us.
Gs31810Unsupported platform
rs137852689(C;C)9.1Lipoid congenital adrenal hyperplasia (LCAH); treatment required
rs104894086(A;A)9.1Lipoid congenital adrenal hyperplasia (LCAH); treatment required
rs137852690(T;T)9.1Lipoid congenital adrenal hyperplasia (LCAH); treatment required
rs104894087(A;A)9.1Lipoid congenital adrenal hyperplasia (LCAH); treatment required
rs193922393(-;-)9.1Lipoid congenital adrenal hyperplasia (LCAH); treatment required
rs104894089(A;A)9.1Lipoid congenital adrenal hyperplasia (LCAH); treatment required
rs786205451(A;A)9.1Epidermolysis bullosa (predicted)
rs387907235(T;T)9.1Lipoid congenital adrenal hyperplasia (LCAH); treatment required
... further results