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Gs315

From SNPedia
Gs315
Magnitude 2
Repute Good
Summary Reduced risk of PD in a haplotype with the C2 variant in the TF gene
Criteria Gs315/criteria



A protective association was found (OR=0.83, 95% CI: 0.71-0.96) between Parkinson's Disease and a haplotype composed of the A allele at rs1880669 and the T allele at rs1049296 in transferrin (TF) in 1289 cases and 1391 controls [PMID 24121126]. Note that the SNP rs1049296 was found in combination with other iron SNPs to be related to an increased risk of AD in Gs293.