rs11568818
| Orientation | minus |
| Stabilized | minus |
| Make rs11568818(A;A) |
| Make rs11568818(A;G) |
| Make rs11568818(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 11 |
| Position | 102530930 |
| Gene | MMP7 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs11568818 |
| dbSNP (classic) | rs11568818 |
| ClinGen | rs11568818 |
| ebi | rs11568818 |
| HLI | rs11568818 |
| Exac | rs11568818 |
| Gnomad | rs11568818 |
| Varsome | rs11568818 |
| LitVar | rs11568818 |
| Map | rs11568818 |
| PheGenI | rs11568818 |
| Biobank | rs11568818 |
| 1000 genomes | rs11568818 |
| hgdp | rs11568818 |
| ensembl | rs11568818 |
| geneview | rs11568818 |
| scholar | rs11568818 |
| rs11568818 | |
| pharmgkb | rs11568818 |
| gwascentral | rs11568818 |
| openSNP | rs11568818 |
| 23andMe | rs11568818 |
| SNPshot | rs11568818 |
| SNPdbe | rs11568818 |
| MSV3d | rs11568818 |
| GWAS Ctlg | rs11568818 |
| GMAF | 0.3324 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
[PMID 18798254
] Chinese breast cancer
rs11568818(G;G) significantly worse prognosis (OS HR: 6.7, 95% CI: 2.4-18.6) than patients homozygous for the common allele (A)
[PMID 22113040] [Study on association between single nucleotide polymorphisms of MMP7, MMP8, MMP9 genes and development of gastric cancer and lymph node metastasis]
[PMID 22348060] Association between Polymorphisms in the Promoter Regions of Matrix Metalloproteinases (MMPs) and Risk of Cancer Metastasis: A Meta-Analysis
[PMID 22621753] Higher risk of matrix metalloproteinase (MMP-2, 7, 9) and tissue inhibitor of metalloproteinase (TIMP-2) genetic variants to gallbladder cancer
[PMID 22664146] Association of matrix metalloproteinases (MMP2, MMP7 and MMP9) genetic variants with left ventricular dysfunction in coronary artery disease patients
[PMID 22268124] Allele-specific transactivation of matrix metalloproteinase 7 by FOXA2 and correlation with plasma levels in idiopathic pulmonary fibrosis
[PMID 18648013] Common MMP-7 polymorphisms and breast cancer susceptibility: a multistage study of association and functionality.
[PMID 19435861] No association between matrix metalloproteinase (MMP)-1, MMP-3, and MMP-7 SNPs and endometrial cancer risk.
[PMID 20113256] Matrix metalloproteinase-7 (MMP-7) polymorphism is a risk factor for endometrial cancer susceptibility.
[PMID 20347338] Genetic polymorphisms in MMP7 and reduced serum levels associate with the development of bronchiolitis obliterans syndrome after lung transplantation.
[PMID 22388798] Gene panels to help identify subgroups at high and low risk of coronary heart disease among those randomized to antihypertensive treatment: the GenHAT study.
| GWAS snp | |
|---|---|
| PMID | [PMID 23535732]
|
| Trait | Prostate cancer |
| Title | Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. |
| Risk Allele | A |
| P-val | 2E-11 |
| Odds Ratio | 1.10 [1.06-1.14] |
[PMID 24757528] MMP7 and MMP8 genetic polymorphisms in bladder cancer patients
[PMID 25711032] [Association of matrix metalloproteinases' polymorphisms of MMP3 and MMP9 with development of genital endometriosis]
[PMID 25847246] Association of MMP7-181A/G promoter polymorphism with gastric cancer risk: Influence of nicotine in differential allele-specific transcription via increased phosphorylation of CREB
[PMID 26411806] Associations Between iCOGS Single Nucleotide Polymorphisms and Upgrading in Both Surgical and Active Surveillance Cohorts of Men with Prostate Cancer
[PMID 27620811] Associations between various possible promoter polymorphisms of MMPs genes and endometriosis risk: a meta-analysis.
[PMID 29876234] Association of the MMP7 -181A>G Promoter Polymorphism with Early Onset of Chronic Obstructive Pulmonary Disease.
[PMID 31441739] [Study of associations of polymorphism of matrix metalloproteinases genes with the development of arterial hypertension in men].
[PMID 33351325] [Gene-environment interactions between polymorphic loci of MMPs and obesity in essential hypertension in women.]
