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rs11622475

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 1.5x risk of bipolar disorder
(C;T) 1.1x risk of bipolar disorder
(T;T) 0 normal
ReferenceGRCh38 38.1/141
Chromosome14
Position104042739
GeneTDRD9
is asnp
is mentioned by
dbSNPrs11622475
dbSNP (classic)rs11622475
ClinGenrs11622475
ebirs11622475
HLIrs11622475
Exacrs11622475
Gnomadrs11622475
Varsomers11622475
LitVarrs11622475
Maprs11622475
PheGenIrs11622475
Biobankrs11622475
1000 genomesrs11622475
hgdprs11622475
ensemblrs11622475
geneviewrs11622475
scholarrs11622475
googlers11622475
pharmgkbrs11622475
gwascentralrs11622475
openSNPrs11622475
23andMers11622475
SNPshotrs11622475
SNPdbers11622475
MSV3drs11622475
GWAS Ctlgrs11622475
GMAF0.2314
Max Magnitude0
? (C;C) (C;T) (T;T) 28


rs11622475 has been reported in a large study to be associated with bipolar disorder.

The risk allele (oriented to the dbSNP entry) is (C); the odds ratio associated with heterozygotes is 1.13 (CI 0.89-1.44), and for homozygotes, 1.47 (CI 1.17-1.86). [PMID 17554300OA-icon.png]

GWAS snp
PMID [PMID 21254220OA-icon.png]
Trait
Title Propensity score-based nonparametric test revealing genetic variants underlying bipolar disorder.
Risk Allele
P-val 0.000002
Odds Ratio None None


[PMID 19308021OA-icon.png] Findings from bipolar disorder genome-wide association studies replicate in a Finnish bipolar family-cohort.