rs12184413
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | normal | |
| (C;T) | normal | |
| (T;T) | 0.7x decreased risk for breast cancer |
| Reference | GRCh38 38.1/141 |
| Chromosome | 11 |
| Position | 102518857 |
| Gene | MMP7 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs12184413 |
| dbSNP (classic) | rs12184413 |
| ClinGen | rs12184413 |
| ebi | rs12184413 |
| HLI | rs12184413 |
| Exac | rs12184413 |
| Gnomad | rs12184413 |
| Varsome | rs12184413 |
| LitVar | rs12184413 |
| Map | rs12184413 |
| PheGenI | rs12184413 |
| Biobank | rs12184413 |
| 1000 genomes | rs12184413 |
| hgdp | rs12184413 |
| ensembl | rs12184413 |
| geneview | rs12184413 |
| scholar | rs12184413 |
| rs12184413 | |
| pharmgkb | rs12184413 |
| gwascentral | rs12184413 |
| openSNP | rs12184413 |
| 23andMe | rs12184413 |
| SNPshot | rs12184413 |
| SNPdbe | rs12184413 |
| MSV3d | rs12184413 |
| GWAS Ctlg | rs12184413 |
| GMAF | 0.1354 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 18648013
] rs12184413(T;T) was associated with reduced risk for breast cancer, with an odds ratio of 0.7 (CI: 0.6-0.9), based on a study ultimately totaling over 3,000 cases (and an equal number of controls).
[PMID 18798254] Genetic polymorphisms in the MMP-7 gene and breast cancer survival.
[PMID 19435861] No association between matrix metalloproteinase (MMP)-1, MMP-3, and MMP-7 SNPs and endometrial cancer risk.
