rs12587781
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (G;T) | 1.79x increased risk for narcolepsy in Europeans and 1.34x in Asians | |
| (T;T) | 0 |
| Make rs12587781(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 14 |
| Position | 22530666 |
| Gene | TRA@ |
| is a | snp |
| is | mentioned by |
| dbSNP | rs12587781 |
| dbSNP (classic) | rs12587781 |
| ClinGen | rs12587781 |
| ebi | rs12587781 |
| HLI | rs12587781 |
| Exac | rs12587781 |
| Gnomad | rs12587781 |
| Varsome | rs12587781 |
| LitVar | rs12587781 |
| Map | rs12587781 |
| PheGenI | rs12587781 |
| Biobank | rs12587781 |
| 1000 genomes | rs12587781 |
| hgdp | rs12587781 |
| ensembl | rs12587781 |
| geneview | rs12587781 |
| scholar | rs12587781 |
| rs12587781 | |
| pharmgkb | rs12587781 |
| gwascentral | rs12587781 |
| openSNP | rs12587781 |
| 23andMe | rs12587781 |
| SNPshot | rs12587781 |
| SNPdbe | rs12587781 |
| MSV3d | rs12587781 |
| GWAS Ctlg | rs12587781 |
| GMAF | 0.292 |
| Max Magnitude | 0 |
| ? | (G;G) (G;T) (T;T) | 28 |
|---|---|---|
|
| ||
23andMe blog Each copy of the G version of rs12587781 increased the odds of narcolepsy by 1.79 times in Europeans and 1.34 times in Asians. The G version of rs12587781 showed a trend towards increased odds of narcolepsy for African Americans, but the results were not statistically significant.
[PMID 19412176
] Narcolepsy is strongly associated with the T-cell receptor alpha locus.
