| Geno
|
Mag
|
Summary
|
| (A;A)
|
0
|
common on affy axiom data
|
| (A;G)
|
2
|
associated with higher HDL cholesterol
|
| (G;G)
|
2
|
associated with higher HDL cholesterol
|
G allele is associated with 2.44mg/dl increase in HDL cholesterol (good cholesterol). [PMID 18193043
]
| GWAS snp
|
| PMID
|
[PMID 19060906]
|
| Trait
|
HDL cholesterol
|
| Title
|
Common variants at 30 loci contribute to polygenic dyslipidemia
|
| Risk Allele
|
G
|
| P-val
|
2E-34
|
| Odds Ratio
|
0.23 [0.17-0.29] SD increase
|
| GWAS snp
|
| PMID
|
[PMID 20686565]
|
| Trait
|
|
| Title
|
Biological, clinical and population relevance of 95 loci for blood lipids.
|
| Risk Allele
|
G
|
| P-val
|
0
|
| Odds Ratio
|
13.6400 None
|
[PMID 19951432] Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.
[PMID 20385819] Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration.
[PMID 20385826] Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC).
| GWAS snp
|
| PMID
|
[PMID 22916037]
|
| Trait
|
Metabolite levels
|
| Title
|
Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
|
| Risk Allele
|
|
| P-val
|
9E-13
|
| Odds Ratio
|
NR NR
|
[PMID 24223199] Association of HDL-Related Loci with Age-Related Macular Degeneration and Plasma Lutein and Zeaxanthin: the Alienor Study
[PMID 22815349] Genetic, behavioral, and sociodemographic risk factors for second eye progression in age-related macular degeneration.
| GWAS snp
|
| PMID
|
[PMID 24097068]
|
| Trait
|
HDL cholesterol
|
| Title
|
Discovery and refinement of loci associated with lipid levels.
|
| Risk Allele
|
G
|
| P-val
|
1E-149
|
| Odds Ratio
|
.16 [NR] unit increase
|
]
