rs13042395

Orientation

plus

Stabilized

plus

Make rs13042395(C;C)

Make rs13042395(C;T)

Make rs13042395(T;T)

Reference

GRCh38 38.1/141

Chromosome

20

Position

773867

Gene

SLC52A3

is a	snp
is	mentioned by
dbSNP	rs13042395
dbSNP (classic)	rs13042395
ClinGen	rs13042395
ebi	rs13042395
HLI	rs13042395
Exac	rs13042395
Gnomad	rs13042395
Varsome	rs13042395
LitVar	rs13042395
Map	rs13042395
PheGenI	rs13042395
Biobank	rs13042395
1000 genomes	rs13042395
hgdp	rs13042395
ensembl	rs13042395
geneview	rs13042395
scholar	rs13042395
google	rs13042395
pharmgkb	rs13042395
gwascentral	rs13042395
openSNP	rs13042395
23andMe	rs13042395
SNPshot	rs13042395
SNPdbe	rs13042395
MSV3d	rs13042395
GWAS Ctlg	rs13042395

GMAF

0.1249

Max Magnitude

0

?	(C;C) (C;T) (T;T)	28

rs13042395 is a SNP in the C20orf54 gene.

In a large study of Han Chinese esophageal cancer patients [specifically esophageal squamous cell carcinoma (ESCC)], the rs13042395(T) allele was associated with lowered risk (odds ratio 0.86, p = 1.21 x 10e-11).[1]

In this same study [2], rs13042395(T) was also associated with lower risk for gastric cancer (aka stomach cancer), with an odds ratio of 0.91 (3 x 10e-3).

OMIM	133239
Desc
Variant
Related	also

[PMID 22744421] Replication study of PLCE1 and C20orf54 polymorphism and risk of esophageal cancer in a Chinese population

[PMID 21427165] Genetic variants at 1q22 and 10q23 reproducibly associated with gastric cancer susceptibility in a Chinese population.

[PMID 22037551] A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at 3q13.31 and 5p13.1.

[PMID 22805490] Genetic variation in C20orf54, PLCE1 and MUC1 and the risk of upper gastrointestinal cancers in Caucasian populations.