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rs140504

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 1.4x increased risk for bipolar disorder
(A;G) 1.4x increased risk for bipolar disorder
(G;G) normal risk
ReferenceGRCh38 38.1/141
Chromosome22
Position23285182
GeneBCR, LOC107985554
is asnp
is mentioned by
dbSNPrs140504
dbSNP (classic)rs140504
ClinGenrs140504
ebirs140504
HLIrs140504
Exacrs140504
Gnomadrs140504
Varsomers140504
LitVarrs140504
Maprs140504
PheGenIrs140504
Biobankrs140504
1000 genomesrs140504
hgdprs140504
ensemblrs140504
geneviewrs140504
scholarrs140504
googlers140504
pharmgkbrs140504
gwascentralrs140504
openSNPrs140504
23andMers140504
23andMe allrs140504
SNPshotrs140504
SNPdbers140504
MSV3drs140504
GWAS Ctlgrs140504
GMAF0.2025
Max Magnitude
? (A;A) (A;G) (G;G) 28

rs140504, a SNP in the BCR gene on chromosome 22, has been associated with increased risk for bipolar disorder. The odds ratio for carriers of the minor allele (G) are reported as 1.45 (CI:1.11 - 1.84, p=0.0054) based on a study of 171 Japanese patients.[PMID 15866548]


OMIM125480
DescMAJOR AFFECTIVE DISORDER 1; MAFD1
Variant
Relatedalso