rs140693

minus

Geno	Mag	Summary
(G;G)	0	common in complete genomics

Make rs140693(A;A)

Make rs140693(A;G)

Reference

GRCh38 38.1/142

Chromosome

3

Position

129436608

Gene

MBD4

is a	snp
is	mentioned by
dbSNP	rs140693
dbSNP (classic)	rs140693
ClinGen	rs140693
ebi	rs140693
HLI	rs140693
Exac	rs140693
Gnomad	rs140693
Varsome	rs140693
LitVar	rs140693
Map	rs140693
PheGenI	rs140693
Biobank	rs140693
1000 genomes	rs140693
hgdp	rs140693
ensembl	rs140693
geneview	rs140693
scholar	rs140693
google	rs140693
pharmgkb	rs140693
gwascentral	rs140693
openSNP	rs140693
23andMe	rs140693
SNPshot	rs140693
SNPdbe	rs140693
MSV3d	rs140693
GWAS Ctlg	rs140693

GMAF

0.1253

Max Magnitude

0

?

(A;A) (A;G) (G;G)

28

[PMID 18495292] We observed a significantly decreased risk of lung cancer associated with the

rs140693(A;G) genotype (adjusted OR=0.70, 95% CI=0.52-0.93),
and the combined rs140693 GA/AA variant genotypes (adjusted OR=0.76, 95% CI=0.58-1.00),
compared with the wild-type homozygote rs140693 GG. The reduced lung cancer risk in non-smokers carrying rs140693 GA/AA genotypes was more predominant (adjusted OR=0.56, 95% CI=0.35-0.87)

[PMID 20100009] Single nucleotide polymorphism in the methyl-CpG binding domain 4 Gene and the risk for immune thrombocytopenic purpura in Chinese population

[PMID 21739480] Potentially functional polymorphisms in DNA repair genes and non-small-cell lung cancer survival: A pathway-based analysis

[PMID 16465622 ] Bladder cancer predisposition: a multigenic approach to DNA-repair and cell-cycle-control genes.

[PMID 22505706] Peptidylarginine deiminase type 4 and methyl-CpG binding domain 4 polymorphisms in Chinese patients with rheumatoid arthritis.

[PMID 23027038] The MBD4 Glu346Lys polymorphism is associated with the risk of cervical cancer in a Chinese population.