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rs1445898

From SNPedia

Orientationminus
Stabilizedminus
Make rs1445898(A;A)
Make rs1445898(A;G)
Make rs1445898(G;G)
ReferenceGRCh38 38.1/141
Chromosome5
Position35910427
GeneCAPSL
is asnp
is mentioned by
dbSNPrs1445898
dbSNP (classic)rs1445898
ClinGenrs1445898
ebirs1445898
HLIrs1445898
Exacrs1445898
Gnomadrs1445898
Varsomers1445898
LitVarrs1445898
Maprs1445898
PheGenIrs1445898
Biobankrs1445898
1000 genomesrs1445898
hgdprs1445898
ensemblrs1445898
geneviewrs1445898
scholarrs1445898
googlers1445898
pharmgkbrs1445898
gwascentralrs1445898
openSNPrs1445898
23andMers1445898
SNPshotrs1445898
SNPdbers1445898
MSV3drs1445898
GWAS Ctlgrs1445898
GMAF0.4844
Max Magnitude0
? (A;A) (A;G) (G;G) 28


rs1445898 is associated with some protection from type-1 diabetes in several European populations.[PMID 18563381]

GWAS snp
PMID [PMID 17554260OA-icon.png]
Trait Type 1 diabetes
Title Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
Risk Allele G
P-val 0.0000079999999999999996
Odds Ratio 1.12 [1.06-1.19]


[PMID 18556337OA-icon.png] Impact of diabetes susceptibility loci on progression from pre-diabetes to diabetes in at-risk individuals of the diabetes prevention trial-type 1 (DPT-1).


[PMID 18927125OA-icon.png] IFIH1 polymorphisms are significantly associated with type 1 diabetes and IFIH1 gene expression in peripheral blood mononuclear cells.


[PMID 19956101OA-icon.png] Overview of the Rapid Response data.


[PMID 19956106OA-icon.png] Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families.


[PMID 19956109OA-icon.png] The Type I Diabetes Genetics Consortium 'Rapid Response' family-based candidate gene study: strategy, genes selection, and main outcome.