||common in complete genomics
rs17222842, also known as SG13S35, is an ALOX5AP gene SNP that has been defined as part of a haplotype potentially associated with risk for myocardial infarction or ischemic stroke. Details of this haplotype and several related studies are on the ALOX5AP page.
[PMID 19130089] Genetic effects in the leukotriene biosynthesis pathway and association with atherosclerosis.
[PMID 19361804] 5-Lipoxygenase activating protein (ALOX5AP) gene variants associate with the presence of xanthomas in familial hypercholesterolemia.
[PMID 19751821] Oxidative risk for atherothrombotic cardiovascular disease.
[PMID 27893808] Common Polymorphisms in the 5-Lipoxygenase Pathway and Risk of Incident Myocardial Infarction: A Danish Case-Cohort Study.