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rs17646665

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 0 common/normal
(A;G) 3.9 Moderately reduced risk for Alzheimer's (~0.6x)
(G;G) 4.2 Reduced risk for Alzheimer's (~0.33x?)
ReferenceGRCh38.p2 38.2/147
Chromosome1
Position109369429
GeneSORT1
is asnp
is mentioned by
dbSNPrs17646665
dbSNP (classic)rs17646665
ClinGenrs17646665
ebirs17646665
HLIrs17646665
Exacrs17646665
Gnomadrs17646665
Varsomers17646665
LitVarrs17646665
Maprs17646665
PheGenIrs17646665
Biobankrs17646665
1000 genomesrs17646665
hgdprs17646665
ensemblrs17646665
geneviewrs17646665
scholarrs17646665
googlers17646665
pharmgkbrs17646665
gwascentralrs17646665
openSNPrs17646665
23andMers17646665
23andMe allrs17646665
SNPshotrs17646665
SNPdbers17646665
MSV3drs17646665
GWAS Ctlgrs17646665
Max Magnitude4.2
? (A;A) (A;G) (G;G) 28


[PMID 27392867OA-icon.png] A Genetic Variant of the Sortilin 1 Gene is Associated with Reduced Risk of Alzheimer's Disease. Minor Allele (G) associated with reduced risk (OR 0.6x, CI: 0.4-0.8) for Alzheimer's Disease; it is possible that the reported association could be restricted to a Swedish/Scandinavian population.