||common on affy axiom data
rs17824933 is a SNP in the region of the CD6 gene.
A large study (~5,000 patients) found an increased risk for multiple sclerosis associated with rs17824933; the odds ratio for the minor allele was reported as 1.18 (CI: 1.07-1.30, p=3.79x10(-9)).10.1038/ng.401
||Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci
[PMID 19825846] Genome-wide analysis of allelic expression imbalance in human primary cells by high throughput transcriptome resequencing
[PMID 20430450] Validation of the CD6 and TNFRSF1A loci as risk factors for multiple sclerosis in Spain
[PMID 21552549] The Genetic Association of Variants in CD6, TNFRSF1A and IRF8 to Multiple Sclerosis: A Multicenter Case-Control Study
[PMID 20405052] The effect of single nucleotide polymorphisms from genome wide association studies in multiple sclerosis on gene expression.
[PMID 21849685] The CD6 multiple sclerosis susceptibility allele is associated with alterations in CD4+ T cell proliferation.
[PMID 23638056] Fine Mapping and Functional Analysis of the Multiple Sclerosis Risk Gene CD6
[PMID 26844569] The Link between CD6 and Autoimmunity: Genetic and Cellular Associations.