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rs17864092

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(T;T) 0 common in complete genomics
Make rs17864092(C;C)
Make rs17864092(C;T)
ReferenceGRCh38 38.1/141
Chromosome7
Position126999550
GeneGRM8
is asnp
is mentioned by
dbSNPrs17864092
dbSNP (classic)rs17864092
ClinGenrs17864092
ebirs17864092
HLIrs17864092
Exacrs17864092
Gnomadrs17864092
Varsomers17864092
LitVarrs17864092
Maprs17864092
PheGenIrs17864092
Biobankrs17864092
1000 genomesrs17864092
hgdprs17864092
ensemblrs17864092
geneviewrs17864092
scholarrs17864092
googlers17864092
pharmgkbrs17864092
gwascentralrs17864092
openSNPrs17864092
23andMers17864092
SNPshotrs17864092
SNPdbers17864092
MSV3drs17864092
GWAS Ctlgrs17864092
GMAF0.107
Max Magnitude0
? (C;C) (C;T) (T;T) 28


rs17864092 is a SNP in the glutamate receptor, metabotropic 8 GRM8 gene, encoding a metabotropic receptor for glutamate, a major excitatory neurotransmitter in the central nervous system.

A genome-wide association study and an accompanying meta-analysis found some evidence for SNPs in the GRM8 gene, most notably rs17864092, and trait depression (p = 5 x 10e-6).[PMID 20800221OA-icon.png]