rs1800469(C;C)
From SNPedia
| lower TGF-β1 levels, higher risk for COPD? |
| Is a | genotype |
| of | rs1800469 |
| Gene | TGFB1, B9D2 |
| Chromosome | 19 |
| Position | 41,354,391 |
| mentioned | by |
| Magnitude | 1 |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 1 | lower TGF-β1 levels, higher risk for COPD? |
| (C;T) | 1 | slightly higher TGF-β1 levels, higher risk for COPD? |
| (T;T) | 1 | higher TGF-β1 levels |
This normal C version significantly reduces TGF-β1 levels by allowing AP1 to downregulate TGF-β1 production.
