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rs1800750

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) higher acute otitis risk
(A;G) normal risk
(G;G) 0 normal risk
ReferenceGRCh38 38.1/141
Chromosome6
Position31575186
GeneTNF
is asnp
is mentioned by
dbSNPrs1800750
dbSNP (classic)rs1800750
ClinGenrs1800750
ebirs1800750
HLIrs1800750
Exacrs1800750
Gnomadrs1800750
Varsomers1800750
LitVarrs1800750
Maprs1800750
PheGenIrs1800750
Biobankrs1800750
1000 genomesrs1800750
hgdprs1800750
ensemblrs1800750
geneviewrs1800750
scholarrs1800750
googlers1800750
pharmgkbrs1800750
gwascentralrs1800750
openSNPrs1800750
23andMers1800750
SNPshotrs1800750
SNPdbers1800750
MSV3drs1800750
GWAS Ctlgrs1800750
GMAF0.01331
Max Magnitude0
? (A;A) (A;G) (G;G) 28


rs1800750, a SNP located at position -376 of the TNF gene, has been linked to increased risk for recurrent acute otitis in a study of 348 children. The (adjusted) odds ratio is 3.06 for (G;G) genotypes (p=0.07).[PMID 17908769]


[PMID 19559392OA-icon.png] A candidate gene association study of 77 polymorphisms in migraine


[PMID 20459604OA-icon.png] Large-scale association analysis of TNF/LTA gene region polymorphisms in type 2 diabetes


[PMID 16846490OA-icon.png] Lemierre's syndrome and genetic polymorphisms: a case report.


[PMID 16872485OA-icon.png] Three allele combinations associated with multiple sclerosis.


[PMID 17216494] Genetic variation in tumor necrosis factor and lymphotoxin-alpha (TNF-LTA) and breast cancer risk.


[PMID 18194515OA-icon.png] Polymorphisms of TNF-enhancer and gene for FcgammaRIIa correlate with the severity of falciparum malaria in the ethnically diverse Indian population.


[PMID 18513389OA-icon.png] New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background.


[PMID 18676870OA-icon.png] Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in China.


[PMID 18805939OA-icon.png] Functional genetic polymorphisms and female reproductive disorders: part II--endometriosis.


[PMID 18936436OA-icon.png] Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994.


[PMID 19131662OA-icon.png] A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients.


[PMID 19143814OA-icon.png] Several loci in the HLA class III region are associated with T1D risk after adjusting for DRB1-DQB1.


[PMID 19167443OA-icon.png] Family-based analysis of tumor necrosis factor and lymphotoxin-alpha tag polymorphisms with type 1 diabetes in the population of South Croatia.


[PMID 19281305OA-icon.png] Tumor necrosis factor and lymphotoxin-alpha polymorphisms and severe malaria in African populations.


[PMID 19330901OA-icon.png] Association of 77 polymorphisms in 52 candidate genes with blood pressure progression and incident hypertension: the Women's Genome Health Study.


[PMID 19505919OA-icon.png] Toll-like receptor signaling pathway variants and prostate cancer mortality.


[PMID 19619703OA-icon.png] Association of genetic variants with the metabolic syndrome in 20,806 white women: The Women's Health Genome Study.


[PMID 20078877OA-icon.png] Gene polymorphisms in association with emerging cardiovascular risk markers in adult women.


[PMID 20459687OA-icon.png] Candidate malaria susceptibility/protective SNPs in hospital and population-based studies: the effect of sub-structuring.


[PMID 21385363OA-icon.png] Polymorphisms in genes controlling inflammation and tissue repair in rheumatoid arthritis: a case control study.


[PMID 24151497OA-icon.png] Association Analysis of IL10, TNF-α, and IL23R-IL12RB2 SNPs with Behçet's Disease Risk in Western Algeria


[PMID 22711844] SNPs in the TNF-alpha gene promoter associated with Behcet's disease in Moroccan patients.


[PMID 22808100OA-icon.png] Functional differences exist between TNFalpha promoters encoding the common -237G SNP and the rarer HLA-B*5701-linked A variant.


[PMID 26448013OA-icon.png] High Incidence of Malaria Along the Sino-Burmese Border Is Associated With Polymorphisms of CR1, IL-1A, IL-4R, IL-4, NOS, and TNF, But Not With G6PD Deficiency


[PMID 29497291OA-icon.png] TNF promoter polymorphisms are associated with genetic susceptibility in COPD secondary to tobacco smoking and biomass burning.