rs1800750
Orientation | plus |
Stabilized | plus |
Geno | Mag | Summary |
---|---|---|
(A;A) | higher acute otitis risk | |
(A;G) | normal risk | |
(G;G) | 0 | normal risk |
Reference | GRCh38 38.1/141 |
Chromosome | 6 |
Position | 31575186 |
Gene | TNF |
is a | snp |
is | mentioned by |
dbSNP | rs1800750 |
dbSNP (classic) | rs1800750 |
ClinGen | rs1800750 |
ebi | rs1800750 |
HLI | rs1800750 |
Exac | rs1800750 |
Gnomad | rs1800750 |
Varsome | rs1800750 |
LitVar | rs1800750 |
Map | rs1800750 |
PheGenI | rs1800750 |
Biobank | rs1800750 |
1000 genomes | rs1800750 |
hgdp | rs1800750 |
ensembl | rs1800750 |
geneview | rs1800750 |
scholar | rs1800750 |
rs1800750 | |
pharmgkb | rs1800750 |
gwascentral | rs1800750 |
openSNP | rs1800750 |
23andMe | rs1800750 |
SNPshot | rs1800750 |
SNPdbe | rs1800750 |
MSV3d | rs1800750 |
GWAS Ctlg | rs1800750 |
GMAF | 0.01331 |
Max Magnitude | 0 |
? | (A;A) (A;G) (G;G) | 28 |
---|---|---|
|
rs1800750, a SNP located at position -376 of the TNF gene, has been linked to increased risk for recurrent acute otitis in a study of 348 children. The (adjusted) odds ratio is 3.06 for (G;G) genotypes (p=0.07).[PMID 17908769]
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[PMID 19131662] A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients.
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[PMID 19505919] Toll-like receptor signaling pathway variants and prostate cancer mortality.
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[PMID 20459687] Candidate malaria susceptibility/protective SNPs in hospital and population-based studies: the effect of sub-structuring.
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[PMID 24151497] Association Analysis of IL10, TNF-α, and IL23R-IL12RB2 SNPs with Behçet's Disease Risk in Western Algeria
[PMID 22711844] SNPs in the TNF-alpha gene promoter associated with Behcet's disease in Moroccan patients.
[PMID 22808100] Functional differences exist between TNFalpha promoters encoding the common -237G SNP and the rarer HLA-B*5701-linked A variant.
[PMID 26448013] High Incidence of Malaria Along the Sino-Burmese Border Is Associated With Polymorphisms of CR1, IL-1A, IL-4R, IL-4, NOS, and TNF, But Not With G6PD Deficiency
[PMID 29497291] TNF promoter polymorphisms are associated with genetic susceptibility in COPD secondary to tobacco smoking and biomass burning.