rs1801222
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (T;T) | 0 | common in clinvar |
| Make rs1801222(C;C) |
| Make rs1801222(C;T) |
| Reference | GRCh38 38.1/142 |
| Chromosome | 10 |
| Position | 17114152 |
| Gene | CUBN |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1801222 |
| dbSNP (classic) | rs1801222 |
| ClinGen | rs1801222 |
| ebi | rs1801222 |
| HLI | rs1801222 |
| Exac | rs1801222 |
| Gnomad | rs1801222 |
| Varsome | rs1801222 |
| LitVar | rs1801222 |
| Map | rs1801222 |
| PheGenI | rs1801222 |
| Biobank | rs1801222 |
| 1000 genomes | rs1801222 |
| hgdp | rs1801222 |
| ensembl | rs1801222 |
| geneview | rs1801222 |
| scholar | rs1801222 |
| rs1801222 | |
| pharmgkb | rs1801222 |
| gwascentral | rs1801222 |
| openSNP | rs1801222 |
| 23andMe | rs1801222 |
| SNPshot | rs1801222 |
| SNPdbe | rs1801222 |
| MSV3d | rs1801222 |
| GWAS Ctlg | rs1801222 |
| GMAF | 0.2305 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
| GWAS snp | |
|---|---|
| PMID | [PMID 23824729 ]
|
| Trait | Homocysteine levels |
| Title | Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease. |
| Risk Allele | A |
| P-val | 8E-10 |
| Odds Ratio | .05 [0.032-0.059] unit increase |
[PMID 16385451] A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
| GWAS snp | |
|---|---|
| PMID | [PMID 19744961]
|
| Trait | Folate pathway vitamin levels |
| Title | Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway. |
| Risk Allele | |
| P-val | 3E-9 |
| Odds Ratio | .05 [0.030-0.070] unit decrease |
| ClinVar | |
|---|---|
| Risk | rs1801222(C;C) |
| Alt | rs1801222(C;C) |
| Reference | Rs1801222(T;T) |
| Significance | Non-pathogenic |
| Disease | Megaloblastic anemia |
| Variation | info |
| Gene | CUBN |
| CLNDBN | Megaloblastic anemia |
| Reversed | 1 |
| HGVS | NC_000010.10:g.17156151A>G |
| CLNSRC | |
| CLNACC | RCV000380325.1, |
[PMID 31641537] The association of megalin and cubilin genetic variants with serum levels of 25-hydroxvitamin D and the incidence of acute coronary syndrome in Egyptians: A case control study.
