rs1861046(G;G)
From SNPedia
| Is a | genotype |
| of | rs1861046 |
| Gene | C1QTNF7, LOC101929095 |
| Chromosome | 4 |
| Position | 15,396,282 |
| mentioned | by |
| Magnitude | 1 |
| Geno | Mag | Summary |
|---|---|---|
| (G;G) | 1 |
Conduct disorder (CD) is one of the most prevalent childhood psychiatric conditions, and is associated with a number of serious concomitant and future problems. CD symptomatology is known to have a considerable genetic component, with heritability estimates in the range of 50%.
Four SNPs reached genome-wide significance with CD symptom count, based on P < 5x10^-8 Two of these SNPs (rs16891867 and rs1861046) were in the gene C1QTNF7 (C1q and tumor necrosis factor-related protein 7). These SNPs were in high LD (r^2=0.97). The other top two SNPs meeting genome-wide significance were intergenic and located on chromosomes 11 and 13. Alleles A/G were found to be associated with CD symptom count or CD case status.
